Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.57 |
| ▸ | HTR3A | P46098 | 4/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319265 | 0.90 | HTR4 (0.70) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7330354 | 0.89 | HTR4 (0.69) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL14256387 | 0.89 | HTR4 (0.52) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL4887786 | 0.79 | HTR4 (0.76) | HTR4DRD2 | |
| SCHEMBL8292934 | 0.78 | HTR3A (0.80) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL4891851 | 0.78 | HTR4 (0.74) | HTR4DRD2 | |
| SCHEMBL8292933 | 0.78 | HTR4 (0.67) | HTR4DRD2 | |
| SCHEMBL5426192 | 0.77 | HTR4 (0.51) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL4887897 | 0.77 | HTR4 (0.51) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL4890493 | 0.77 | HTR4 (0.66) | HTR4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007600-A2 | NOVEL METHODS USING AMINOBENZOIC ACID COMPOUNDS | EISAI CO., LTD. (JP) | 2005-01-27 | — | — | WO | disclosed |