Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294431 | 0.94 | KDM4E (0.44) | KDM4EALDH1A1GAACYP1A2CYP2D6 | |
| SCHEMBL6254144 | 0.82 | EGLN1 (0.44) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL1491698 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1GAACYP1A2CYP2D6 | |
| SCHEMBL1491696 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1GAACYP1A2CYP2D6 | |
| SCHEMBL32677077 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1GAACYP1A2CYP2D6 | |
| SCHEMBL6866846 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1GAACYP1A2CYP2D6 | |
| SCHEMBL29707282 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1GAACYP1A2CYP2D6 | |
| SCHEMBL29715383 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1GAACYP1A2CYP2D6 | |
| SCHEMBL13604128 | 0.79 | NAMPT (0.42) | KDM4EALDH1A1GAACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL30665771 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1GAACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056013-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |