Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866846 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| SCHEMBL29715383 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| SCHEMBL32677077 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| SCHEMBL1491696 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| SCHEMBL1491698 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL30665771 | 0.98 | KDM4E (0.55) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL10749367 | 0.98 | KDM4E (0.55) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL8724704 | 0.98 | KDM4E (0.55) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL14059291 | 0.98 | KDM4E (0.55) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| SCHEMBL27478435 | 0.85 | MEN1 (0.47) | KMT2AMEN1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583857-B2 | Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2026-03-24 | — | — | US | disclosed |
| US-20260049060-A1 | TETRAHYDROISOQUINOLINYLMETHYLBENZAMIDE COMPOUNDS | NATIONAL HEALTH RES INST (TW) | 2026-02-19 | — | — | US | disclosed |
| US-20250011317-A1 | ANTI-PROLIFERATIVE AGENTS | PHEON THERAPEUTICS LTD (GB) | 2025-01-09 | — | — | US | disclosed |
| US-20240109916-A1 | CYTOTOXIC AGENTS | PHEON THERAPEUTICS LTD (GB) | 2024-04-04 | — | — | US | disclosed |
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2024-02-27 | — | — | US | disclosed |
| US-20240002379-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2024-01-04 | — | — | US | disclosed |
| US-11466032-B2 | Cytotoxic agents | FEMTOGENIX LIMITED | 2022-10-11 | — | — | US | disclosed |
| CN-114615976-A | Kappa opioid receptor peptide amide agonists | 人福医药美国公司 | 2022-06-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260049060-A1 | TETRAHYDROISOQUINOLINYLMETHYLBENZAMIDE COMPOUNDS | OPRK1, OPRD1, OPRM1 | KDM4E 4158/4885ALDH1A1 1415/4885CYP1A2 482/4885 |
| US-20240109916-A1 | CYTOTOXIC AGENTS | MKI67, TP53, NFATC1 | KDM4E 4398/4885ALDH1A1 1520/4885CYP1A2 2636/4885 |
| US-11466032-B2 | Cytotoxic agents | MKI67, TP53, NFATC1 | KDM4E 4398/4885ALDH1A1 1520/4885CYP1A2 2636/4885 |
| US-12583857-B2 | Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | CNR1, MTNR1B, MTNR1A | KDM4E 1922/4885ALDH1A1 1463/4885CYP1A2 2042/4885 |
| US-20250011317-A1 | ANTI-PROLIFERATIVE AGENTS | CCND2, BRD2, CCND3 | KDM4E 1454/4885ALDH1A1 3182/4885CYP1A2 2468/4885 |
| US-20240002379-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | TUBA1C, MTX2, CCNO | KDM4E 3451/4885ALDH1A1 2285/4885CYP1A2 1717/4885 |
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | MKI67, CCND2, CCND1 | KDM4E 684/4885ALDH1A1 443/4885CYP1A2 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.