Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 7/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253225 | 1.00 | TDP1 (0.48) | TDP1CTSSCTSKPOLBSCN9A | |
| SCHEMBL8293698 | 0.92 | TDP1 (0.47) | TDP1CTSSCTSKSCN9ACXCR3 | |
| SCHEMBL6251076 | 0.92 | TDP1 (0.47) | TDP1CTSSCTSKSCN9ACXCR3 | |
| SCHEMBL8294726 | 0.92 | TDP1 (0.47) | TDP1CTSSCTSKSCN9ACXCR3 | |
| SCHEMBL8293705 | 0.91 | CTSS (0.42) | TDP1CTSSCTSKPOLBSCN9A | |
| SCHEMBL8293702 | 0.91 | CTSS (0.42) | TDP1CTSSCTSKPOLBSCN9A | |
| SCHEMBL6298469 | 0.89 | TDP1 (0.56) | TDP1CTSSCTSKSCN9ACXCR3 | |
| SCHEMBL8294401 | 0.89 | TDP1 (0.56) | TDP1CTSSCTSKSCN9ACXCR3 | |
| SCHEMBL4888640 | 0.86 | TDP1 (0.52) | TDP1CTSSCTSKSCN9ACXCR3 | |
| SCHEMBL4888653 | 0.86 | TDP1 (0.52) | TDP1CTSSCTSKSCN9ACXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056013-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |