Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293705 | 0.97 | CTSS (0.42) | CTSSCTSKSCN9ATDP1SCN10A | |
| SCHEMBL8293703 | 0.93 | KLK5 (0.42) | CTSSCTSKSCN9ATDP1SCN10A | |
| SCHEMBL8294728 | 0.91 | TDP1 (0.48) | CTSSCTSKSCN9ATDP1ACE | |
| SCHEMBL6253225 | 0.91 | TDP1 (0.48) | CTSSCTSKSCN9ATDP1ACE | |
| SCHEMBL8294434 | 0.90 | SCN9A (0.41) | CTSSCTSKSCN9ATDP1SCN10A | |
| SCHEMBL8293704 | 0.90 | KLK5 (0.42) | CTSSCTSKSCN9ATDP1SCN10A | |
| SCHEMBL8294435 | 0.87 | SCN9A (0.41) | CTSSCTSKSCN9ATDP1SCN10A | |
| SCHEMBL6249845 | 0.87 | SCN9A (0.41) | CTSSCTSKSCN9ATDP1SCN10A | |
| SCHEMBL8294726 | 0.83 | TDP1 (0.47) | CTSSCTSKSCN9ATDP1KLK5 | |
| SCHEMBL6251076 | 0.83 | TDP1 (0.47) | CTSSCTSKSCN9ATDP1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056013-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |