Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 7/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292927 | 0.83 | HTR4 (0.57) | HTR4DRD2CYP1A2CYP3A4ADRA2A | |
| SCHEMBL14265617 | 0.80 | HTR4 (0.56) | HTR4DRD2ADRA2AADRA2BADRA2C | |
| SCHEMBL8292933 | 0.80 | HTR4 (0.67) | HTR4DRD2 | |
| SCHEMBL4887786 | 0.77 | HTR4 (0.76) | HTR4DRD2 | |
| Hydrochloric Acid SCHEMBL4891851 | 0.76 | HTR4 (0.74) | HTR4DRD2 | |
| SCHEMBL8294091 | 0.74 | HTR4 (0.57) | HTR4DRD2CYP2D6CYP2C9HTR3A | |
| SCHEMBL4887530 | 0.73 | HTR4 (0.73) | HTR4DRD2 | |
| SCHEMBL15650737 | 0.73 | HTR4 (0.83) | HTR4DRD2CYP1A2CYP3A4ADRA2A | |
| SCHEMBL4892940 | 0.73 | HTR4 (0.71) | HTR4DRD2 | |
| Hydrochloric Acid SCHEMBL4893647 | 0.73 | HTR4 (0.71) | HTR4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007600-A2 | NOVEL METHODS USING AMINOBENZOIC ACID COMPOUNDS | EISAI CO., LTD. (JP) | 2005-01-27 | — | — | WO | disclosed |