Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13063349 | 0.82 | IDO1 (0.30) | IDO1TDO2 | |
| SCHEMBL22342246 | 0.79 | IDO1 (0.33) | DPP4DPP7IDO1TDO2 | |
| SCHEMBL317021 | 0.78 | — | — | |
| SCHEMBL20204157 | 0.77 | CTSL (0.39) | DPP4DPP7IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL28855937 | 0.76 | ADH1B (0.38) | — | |
| SCHEMBL12203977 | 0.76 | DPP4 (0.34) | DPP4DPP7IDO1TDO2 | |
| SCHEMBL1715994 | 0.76 | DPP4 (0.34) | DPP4DPP7IDO1TDO2 | |
| SCHEMBL910374 | 0.75 | KCNQ3 (0.33) | DPP4DPP7IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL1714608 | 0.74 | DPP4 (0.33) | DPP4DPP7IDO1TDO2 | |
| SCHEMBL15359375 | 0.74 | CTSL (0.33) | DPP4DPP7IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003099-A2 | PYRIMIDINES USEFUL AS MODULATORS OF VOLTAGE-GATED ION CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-01-13 | — | — | WO | disclosed |