Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165538 | 0.85 | PSMB5 (0.64) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL607257 | 0.82 | NMT2 (0.53) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL606965 | 0.80 | FAAH (0.46) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL10245379 | 0.78 | PSMB5 (0.66) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL26032021 | 0.77 | FAAH (0.54) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL20542713 | 0.74 | LPAR3 (0.62) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL20542958 | 0.74 | LPAR3 (0.62) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL20543107 | 0.74 | LPAR3 (0.62) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL20542957 | 0.74 | LPAR3 (0.62) | PLA2G10FAAHMEN1MAPK1KMT2A | |
| SCHEMBL20542956 | 0.74 | LPAR3 (0.62) | PLA2G10FAAHMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021558-A2 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2005-03-10 | — | — | WO | disclosed |