Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604122 | 0.95 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8292037 | 0.82 | GRIA1 (0.44) | ALDH1A1TSHRPOLBGRIA1GRIA2 | |
| SCHEMBL8292026 | 0.82 | MAPT (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8291560 | 0.79 | MAPT (0.57) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8291563 | 0.76 | MAPT (0.41) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8903008 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8129450 | 0.74 | GRIA1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8911834 | 0.72 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8300289 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL1192979 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676397-B1 | Oxopyridinylquinoxaline derivatives | SHIONOGI & CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| CN-1044241-C | Oxopyridinylquinoxaline derivative | SHIONOGI & CO (JP) | 1999-07-21 | — | — | CN | disclosed |
| US-5677305-A | NERVOUS SYSTEM DISORDERS | SHIONOGI & CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| CN-1123792-A | Oxopyridinylquinoxaline derivative | SHIONOGI & CO (JP) | 1996-06-05 | — | — | CN | disclosed |
| EP-0676397-A1 | Oxopyridinylquinoxaline derivatives | SHIONOGI & CO., LTD. (JP) | 1995-10-11 | — | — | EP | disclosed |