Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28873119 | 0.88 | RAB9A (0.51) | RAB9ANPC1PTPN1ALDH1A1HPGD | |
| SCHEMBL5349959 | 0.84 | RAB9A (0.59) | RAB9ANPC1PTPN1ALDH1A1HPGD | |
| SCHEMBL12327392 | 0.77 | KDM4E (0.46) | HSD17B10MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL6598838 | 0.77 | RAB9A (1.00) | RAB9ANPC1PTPN1ALDH1A1HPGD | |
| Bromide SCHEMBL30883373 | 0.75 | RAB9A (0.97) | RAB9ANPC1PTPN1ALDH1A1HPGD | |
| SCHEMBL23374469 | 0.75 | MBOAT4 (0.38) | RAB9ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL26046013 | 0.75 | NPSR1 (0.43) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL11636011 | 0.74 | KDM4E (0.55) | RAB9ANPC1PTPN1ALDH1A1HPGD | |
| SCHEMBL28950047 | 0.73 | RAB9A (0.91) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2161557 | 0.73 | RAB9A (0.57) | RAB9ANPC1PTPN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508469-B1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5493024-A | 1,2-DIARYL-2-PROPEN-1-ONE CHEMICAL INTERMEDIATE COMPOUND | DOWELANCO (US) | 1996-02-20 | — | — | US | disclosed |
| US-5324837-A | 3,4-disubstituted-4,5-dihydro-1H-pyrazoles and a method of preparation | DOWELANCO (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0508469-A1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1992-10-14 | — | — | EP | disclosed |