Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294260 | 0.88 | HTT (0.44) | MAPK14SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8294285 | 0.86 | PRMT5 (0.44) | MAPK14SMN1; SMN2ALDH1A1PRMT5TYRO3 | |
| SCHEMBL8295541 | 0.85 | SMYD3 (0.48) | ADRB2SMYD3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8294190 | 0.84 | NPC1 (0.58) | SMYD3SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8294294 | 0.84 | SMYD3 (0.47) | ADRB2SMYD3SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8295046 | 0.83 | NPC1 (0.47) | SMYD3SMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL8295517 | 0.80 | SMYD3 (0.48) | ADRB2SMYD3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8295465 | 0.79 | DPP4 (0.57) | SMYD3RAB9ADPP4KCNH2DPP7 | |
| SCHEMBL8296819 | 0.79 | NR3C1 (0.36) | SMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL8296585 | 0.78 | NR1H4 (0.41) | PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |