Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 7/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296818 | 0.88 | SYK (0.38) | SMN1; SMN2ALDH1A1F2HRH3POLB | |
| SCHEMBL8295492 | 0.81 | FASN (0.41) | OPRD1F2ATM | |
| SCHEMBL8296560 | 0.81 | HSD17B1 (0.37) | SMN1; SMN2HSD17B1HSD17B2F2POLB | |
| SCHEMBL8296568 | 0.81 | F2 (0.36) | NR3C1F2ATM | |
| SCHEMBL8296607 | 0.79 | ADRB2 (0.46) | SMN1; SMN2ALDH1A1POLBRAB9A | |
| SCHEMBL8295037 | 0.78 | LMNA (0.47) | SMN1; SMN2AAK1 | |
| SCHEMBL8296585 | 0.78 | NR1H4 (0.41) | F2 | |
| SCHEMBL8294285 | 0.77 | PRMT5 (0.44) | SMN1; SMN2ALDH1A1POLBPRSS1ATM | |
| SCHEMBL8294228 | 0.76 | F2 (0.34) | F2PRSS1 | |
| SCHEMBL8295090 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2ACKR3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |