Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8295032 | 0.90 | EPHX1 (0.39) | TRPM8DPP4F2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8295030 | 0.88 | EPHX1 (0.43) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL8296559 | 0.84 | TRPM8 (0.41) | TRPM8DPP4DPP7KCNH2F2 | |
| SCHEMBL8295906 | 0.84 | TRPM8 (0.41) | TRPM8DPP4DPP7KCNH2F2 | |
| Hydrochloric Acid SCHEMBL6243770 | 0.83 | TRPM8 (0.40) | TRPM8DPP4DPP7KCNH2F2 | |
| Hydrochloric Acid SCHEMBL6243767 | 0.83 | TRPM8 (0.40) | TRPM8DPP4DPP7KCNH2F2 | |
| SCHEMBL8294323 | 0.82 | KMT2A (0.43) | KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL8295905 | 0.80 | F2 (0.41) | KCNH2F2L3MBTL1 | |
| SCHEMBL8294266 | 0.80 | F2 (0.41) | DPP4KCNH2KMT2AF2L3MBTL1 | |
| SCHEMBL8296774 | 0.78 | DPP4 (0.46) | DPP4DPP7KCNH2KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |