Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 5/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296830 | 0.90 | TRPM8 (0.44) | F2TRPM8ALDH1A1DPP4ABCC1 | |
| SCHEMBL8295030 | 0.88 | EPHX1 (0.43) | EPHX1ALOX5APFEN1RXRARXRB | |
| SCHEMBL8295894 | 0.85 | ALDH1A1 (0.38) | EPHX1F2ALDH1A1DPP4DPP9 | |
| SCHEMBL8295913 | 0.79 | ALDH1A1 (0.46) | F2ALDH1A1NPSR1HSD11B1 | |
| SCHEMBL8295887 | 0.78 | PARP15 (0.49) | — | |
| SCHEMBL8295504 | 0.78 | F2 (0.41) | EPHX1F2NPSR1HSD11B1 | |
| SCHEMBL1750107 | 0.77 | KMT2A (0.47) | ALDH1A1RXRARXRBRXRGNPC1 | |
| SCHEMBL927089 | 0.77 | ALDH1A1 (0.49) | ALDH1A1RXRARXRBRXRGNPC1 | |
| SCHEMBL8295463 | 0.76 | CA2 (0.42) | POLBSMN1; SMN2 | |
| SCHEMBL8296599 | 0.76 | NPSR1 (0.44) | F2ALDH1A1DPP4NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |