Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297698 | 0.88 | MEN1 (0.47) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8302809 | 0.88 | KMT2A (0.51) | MEN1KMT2ACCNA2CDK2CCNA1 | |
| SCHEMBL8301720 | 0.86 | MEN1 (0.44) | MEN1KMT2ACCNA2CDK2CCNA1 | |
| SCHEMBL8295420 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8297695 | 0.79 | MEN1 (0.46) | MEN1KMT2AALDH1A1HPGDKDM4C | |
| SCHEMBL8297703 | 0.79 | NPC1 (0.44) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL16039994 | 0.78 | MEN1 (0.43) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8296603 | 0.77 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL23835461 | 0.76 | MEN1 (0.39) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2499084 | 0.76 | KMT2A (0.53) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090035313-A1 | Compounds | PFIZER INC. | 2009-02-05 | — | — | US | disclosed |
| WO-2005009965-A1 | NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS | PFIZER LIMITED (GB) | 2005-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090035313-A1 | Compounds | NQO1, NAMPT, NNT | MEN1 532/4885KMT2A 2721/4885KDM4E 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.