Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297882 | 0.93 | HPGD (0.46) | MAPTKDM4ETDP1ALOX15HSD17B10 | |
| SCHEMBL30721723 | 0.89 | HSD17B10 (0.59) | MAPTKDM4ETDP1ALOX15HSD17B10 | |
| SCHEMBL8297850 | 0.84 | KMT2A (0.43) | MAPTKDM4ETDP1ALOX15HSD17B10 | |
| SCHEMBL5700024 | 0.81 | PTK2B (0.59) | MAPTALOX15HSD17B10HPGDCYP1A2 | |
| SCHEMBL4624103 | 0.80 | KDM4E (0.50) | MAPTKDM4ETDP1HSD17B10HPGD | |
| SCHEMBL11663752 | 0.79 | KMT2A (0.63) | MAPTKDM4ETDP1ALOX15HSD17B10 | |
| SCHEMBL10782155 | 0.77 | MAPT (0.58) | MAPTKDM4ETDP1ALOX15HSD17B10 | |
| SCHEMBL29770076 | 0.77 | HPGD (0.79) | MAPTKDM4ETDP1ALOX15HSD17B10 | |
| SCHEMBL29402736 | 0.76 | TSHR (0.59) | MAPTKDM4EALOX15HSD17B10KMT2A | |
| SCHEMBL129359 | 0.76 | TSHR (0.59) | MAPTKDM4EALOX15HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041904-A2 | INHIBITORS OF CORONAVIRUS PROTEASE AND METHODS OF USE THEREOF | FULCRUM PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |