Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | EYA2 | O00167 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22611880 | 0.80 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2PLK1MAPTCYP3A4 | |
| SCHEMBL14581345 | 0.78 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HTTMAPTCYP3A4 | |
| SCHEMBL31005086 | 0.77 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2HTTMAPTCYP3A4 | |
| SCHEMBL8348075 | 0.75 | MAOB (0.60) | ALDH1A1HTTMAPTLMNAATM | |
| SCHEMBL8299121 | 0.74 | KMT2A (0.66) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL14583852 | 0.73 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HTTMAPTCYP3A4 | |
| Nitric Acid SCHEMBL11767779 | 0.73 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| Nitric Acid SCHEMBL11767786 | 0.73 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL17560869 | 0.73 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HTTMAPTCYP3A4 | |
| SCHEMBL19449682 | 0.73 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HTTMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037785-A1 | Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
| WO-2005037779-A2 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037785-A1 | Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases | DNPEP, PREP, DPP4 | ALDH1A1 1472/4885SMN1; SMN2 4098/4885HTT 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.