Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301481 | 0.91 | SMN1; SMN2 (0.55) | ALDH1A1MEN1KMT2ATSHRHPGD | |
| SCHEMBL8299700 | 0.90 | MCHR1 (0.54) | ALDH1A1MEN1KMT2ATSHRHPGD | |
| SCHEMBL8299746 | 0.89 | CACNA1G (0.64) | ALDH1A1MEN1KMT2ATSHRHPGD | |
| SCHEMBL8293878 | 0.85 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2ATSHRHPGD | |
| SCHEMBL8300413 | 0.85 | MEN1 (0.58) | ALDH1A1NPC1MEN1KMT2ATSHR | |
| SCHEMBL8299754 | 0.84 | F10 (0.53) | ALDH1A1TSHRHPGDLMNAMAPT | |
| SCHEMBL8299752 | 0.83 | HPGD (0.55) | ALDH1A1MEN1KMT2ATSHRHPGD | |
| SCHEMBL27416400 | 0.83 | MEN1 (0.55) | ALDH1A1MEN1KMT2ATSHRHPGD | |
| SCHEMBL8293093 | 0.82 | HPGD (0.59) | ALDH1A1MEN1KMT2ATSHRHPGD | |
| SCHEMBL8292110 | 0.82 | MEN1 (0.54) | ALDH1A1MEN1KMT2ATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |