Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297193 | 0.89 | POLB (0.58) | F10MCHR1MAPTTP53KDM4E | |
| SCHEMBL8291728 | 0.87 | HPGD (0.49) | MCHR1KDM4ELMNAHPGDTSHR | |
| SCHEMBL8299700 | 0.87 | MCHR1 (0.54) | F10MCHR1MAPTTP53KDM4E | |
| SCHEMBL8301481 | 0.84 | SMN1; SMN2 (0.55) | MCHR1MAPTTP53HPGDTSHR | |
| SCHEMBL8299253 | 0.84 | ALDH1A1 (0.53) | MCHR1MAPTTP53KDM4ELMNA | |
| SCHEMBL8292060 | 0.83 | KMT2A (0.52) | MCHR1MAPTTP53KDM4ELMNA | |
| SCHEMBL8297286 | 0.81 | HPGD (0.50) | MAPTTP53KDM4ELMNAHPGD | |
| SCHEMBL8301263 | 0.80 | POLB (0.50) | MAPTKDM4ELMNAHPGDTSHR | |
| SCHEMBL8570087 | 0.80 | GAA (0.57) | MCHR1KDM4ELMNAHPGDTSHR | |
| SCHEMBL8293878 | 0.78 | SMN1; SMN2 (0.50) | MCHR1MAPTTP53KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |