Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 4/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591529 | 0.83 | TDP1 (0.50) | KDM4ETSHRUSP2LMNAPOLB | |
| SCHEMBL2713680 | 0.81 | KDM4E (0.44) | KDM4ETSHRUSP2LMNAPOLB | |
| SCHEMBL7671966 | 0.80 | CASP3 (0.50) | TSHRCASP3CA12CA1CA2 | |
| SCHEMBL13140583 | 0.80 | MEN1 (0.55) | KDM4ETSHRUSP2LMNAPOLB | |
| SCHEMBL2712868 | 0.79 | KCNH2 (0.47) | KDM4ETSHRUSP2LMNAPOLB | |
| SCHEMBL29872335 | 0.79 | MEN1 (0.53) | KDM4ETSHRUSP2LMNAPOLB | |
| SCHEMBL16422570 | 0.78 | CASP3 (0.46) | KDM4ETSHRUSP2LMNAPOLB | |
| SCHEMBL31667525 | 0.78 | CACNA1G (0.44) | KDM4ETSHRUSP2LMNAPOLB | |
| SCHEMBL12184819 | 0.77 | CASP3 (0.56) | KDM4ETSHRCASP3CA12CA1 | |
| SCHEMBL770153 | 0.77 | CASP3 (0.54) | CASP3CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |