Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297850 | 0.74 | KMT2A (0.43) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL14645263 | 0.72 | KMT2A (0.49) | KDM4EPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8298515 | 0.70 | KMT2A (0.47) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL8299594 | 0.70 | — | — | |
| SCHEMBL3961199 | 0.67 | MEN1 (0.44) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL31613086 | 0.66 | MEN1 (0.43) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL3788448 | 0.66 | PTK2 (0.38) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL4654073 | 0.65 | KMT2A (0.39) | MAPTPOLBMAPK1KMT2AESR1 | |
| SCHEMBL18165232 | 0.64 | KMT2A (0.50) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL17933786 | 0.63 | KMT2A (0.69) | MAPTPOLBKMT2AALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041904-A2 | INHIBITORS OF CORONAVIRUS PROTEASE AND METHODS OF USE THEREOF | FULCRUM PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |