Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12739396 | 0.85 | ACACB (0.37) | ACACBSIGMAR1GLANPSR1MAPK1 | |
| SCHEMBL1609487 | 0.84 | SMN1; SMN2 (0.39) | ACACBSIGMAR1MAPK1NPC1LMNA | |
| SCHEMBL8271362 | 0.84 | SMN1; SMN2 (0.39) | ACACBSIGMAR1MAPK1NPC1LMNA | |
| SCHEMBL1610669 | 0.79 | ACACB (0.35) | ACACBSIGMAR1MAPK1NPC1S1PR1 | |
| SCHEMBL1828390 | 0.79 | ALDH1A1 (0.41) | ACACBSIGMAR1MAPK1NPC1HTT | |
| SCHEMBL2252368 | 0.76 | MEN1 (0.37) | ACACBSIGMAR1MAPK1NPC1HTT | |
| SCHEMBL8292226 | 0.74 | MAPK1 (0.34) | ACACBSIGMAR1MAPK1NPC1GRM2 | |
| SCHEMBL2247202 | 0.74 | ALDH1A1 (0.43) | ACACBSIGMAR1MAPK1LMNAHTT | |
| SCHEMBL2247475 | 0.74 | LMNA (0.42) | ACACBMAPK1LMNAHTTMAPT | |
| SCHEMBL1828213 | 0.73 | MCHR1 (0.40) | ACACBSIGMAR1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101537-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LTD (GB) | 2004-11-25 | — | — | WO | disclosed |