Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 12/20 | 0.68 |
| ▸ | MMP13 | P45452 | 3/20 | 0.68 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298112 | 0.92 | MMP12 (0.65) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6367899 | 0.88 | MMP12 (0.73) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6141819 | 0.85 | MMP12 (0.71) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL8300026 | 0.81 | MMP12 (0.66) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6141848 | 0.81 | MMP12 (1.00) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6368500 | 0.81 | MMP12 (1.00) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6141835 | 0.81 | MMP12 (1.00) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6142319 | 0.79 | MMP12 (0.68) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6368969 | 0.79 | MMP12 (0.70) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6875493 | 0.78 | MMP12 (0.59) | MMP12MMP13MMP8ABL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003115-A1 | THIOPHENE AMINO ACID DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |