Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 12/20 | 0.66 |
| ▸ | MMP13 | P45452 | 3/20 | 0.66 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367899 | 0.89 | MMP12 (0.73) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6141819 | 0.88 | MMP12 (0.71) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL8301905 | 0.86 | MMP12 (0.78) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL8302059 | 0.86 | MMP12 (0.76) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6882182 | 0.86 | MMP12 (0.57) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL8300028 | 0.86 | MMP12 (0.58) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6371574 | 0.84 | MMP12 (0.80) | MMP12MMP13PDE2APOLBMAPT | |
| SCHEMBL8298112 | 0.83 | MMP12 (0.65) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL8300027 | 0.81 | MMP12 (0.68) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6142319 | 0.80 | MMP12 (0.68) | MMP12MMP13MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003115-A1 | THIOPHENE AMINO ACID DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |