Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.41 |
| ▸ | FNTB | P49356 | 10/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.41 |
| ▸ | BRS3 | P32247 | 3/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | NRAS | P01111 | 1/20 | 0.35 |
| ▸ | HRAS | P01112 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7830292 | 0.84 | CHRM4 (0.42) | BRS3MAOAMAOBACHEPRKAA2 | |
| SCHEMBL7464954 | 0.83 | FNTA (0.45) | FNTAFNTBPGGT1BBRS3ROCK2 | |
| Hydrochloric Acid SCHEMBL8301974 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1BBRS3HSD11B1 | |
| Hydrochloric Acid SCHEMBL7461836 | 0.79 | FNTA (0.41) | FNTAFNTBPGGT1BBRS3ROCK2 | |
| SCHEMBL7466881 | 0.79 | BRS3 (0.48) | FNTAFNTBPGGT1BBRS3ROCK2 | |
| SCHEMBL8310406 | 0.76 | FNTA (0.66) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8299809 | 0.76 | FNTA (0.54) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8420854 | 0.76 | FNTA (0.65) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8301587 | 0.76 | FNTA (0.54) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8420978 | 0.74 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897303-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-02-24 | — | — | EP | disclosed |
| EP-0897303-A4 | — | — | 1999-02-24 | — | — | EP | disclosed |
| WO-1997036605-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |