Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.45 |
| ▸ | FNTB | P49356 | 13/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.43 |
| ▸ | BRS3 | P32247 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7461836 | 0.94 | FNTA (0.41) | FNTAFNTBPGGT1BROCK2BRS3 | |
| SCHEMBL7466881 | 0.89 | BRS3 (0.48) | FNTAFNTBPGGT1BROCK2BRS3 | |
| Hydrochloric Acid SCHEMBL8301974 | 0.84 | FNTA (0.42) | FNTAFNTBPGGT1BROCK2BRS3 | |
| SCHEMBL8300491 | 0.83 | FNTA (0.41) | FNTAFNTBPGGT1BROCK2BRS3 | |
| SCHEMBL7459728 | 0.78 | FNTA (0.42) | FNTAFNTBPGGT1BBRS3 | |
| SCHEMBL7927442 | 0.78 | FNTA (0.46) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL7452346 | 0.77 | FNTA (0.42) | FNTAFNTBPGGT1BBRS3 | |
| SCHEMBL7936033 | 0.77 | KCNH2 (0.48) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7527887 | 0.77 | FNTA (0.71) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL7830292 | 0.77 | CHRM4 (0.42) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891360-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-05-15 | — | — | EP | claimed |
| EP-0891360-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036900-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |