Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.78 |
| ▸ | DRD2 | P14416 | 10/20 | 0.78 |
| ▸ | DRD4 | P21917 | 9/20 | 0.74 |
| ▸ | HTR1A | P08908 | 7/20 | 0.74 |
| ▸ | DRD1 | P21728 | 7/20 | 0.74 |
| ▸ | DRD5 | P21918 | 7/20 | 0.74 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | PRCP | P42785 | 1/20 | 0.66 |
| ▸ | EBP | Q15125 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819670 | 0.92 | DRD2 (0.78) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL7354319 | 0.91 | DRD3 (0.80) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL7316143 | 0.88 | DRD3 (1.00) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL29914667 | 0.83 | DRD2 (1.00) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL3454031 | 0.83 | DRD2 (1.00) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL11638019 | 0.83 | DRD3 (0.76) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL30878617 | 0.83 | DRD3 (0.65) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL21148630 | 0.81 | DRD3 (0.54) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL4827157 | 0.81 | DRD2 (0.87) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL8299573 | 0.80 | DRD2 (0.52) | DRD3DRD2DRD4HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |