Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.52 |
| ▸ | DRD3 | P35462 | 11/20 | 0.52 |
| ▸ | DRD1 | P21728 | 8/20 | 0.50 |
| ▸ | DRD4 | P21917 | 8/20 | 0.50 |
| ▸ | DRD5 | P21918 | 8/20 | 0.50 |
| ▸ | HTR1A | P08908 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912160 | 0.85 | DRD2 (0.66) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL22307922 | 0.85 | DRD2 (0.66) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL23374660 | 0.85 | DRD2 (0.66) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL30878617 | 0.81 | DRD3 (0.65) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL21148630 | 0.80 | DRD3 (0.54) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8300543 | 0.80 | DRD3 (0.78) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL12319791 | 0.78 | DRD2 (0.60) | DRD2DRD3 | |
| SCHEMBL2280294 | 0.78 | QDPR (0.51) | DRD2DRD3 | |
| SCHEMBL14136275 | 0.77 | DRD2 (0.71) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL1003503 | 0.77 | DRD2 (0.73) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |