Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646363 | 1.00 | TK1 (0.39) | TK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL8298155 | 1.00 | TK1 (0.39) | TK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL8304127 | 1.00 | TK1 (0.39) | TK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL8303221 | 0.86 | CYP1A2 (0.39) | TK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL8298156 | 0.85 | TK1 (0.38) | TK1PARP1HSD11B1RNASE1 | |
| SCHEMBL8304128 | 0.85 | TK1 (0.38) | TK1PARP1HSD11B1RNASE1 | |
| SCHEMBL8300811 | 0.85 | TK1 (0.38) | TK1PARP1HSD11B1RNASE1 | |
| SCHEMBL13956884 | 0.78 | DRD2 (0.37) | TK1RNASE1 | |
| SCHEMBL8304914 | 0.72 | SRC (0.43) | — | |
| SCHEMBL8639265 | 0.72 | SRC (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646596-B1 | Nucleic acid binding oligomers having C-branches for therapy and diagnosis | BAYER AG (DE) | 1999-05-26 | — | — | EP | disclosed |
| US-5849893-A | Nucleic acid-binding oligomers possessing C-branching for therapy and diagnostics | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0646596-A1 | Nucleic acid binding oligomers having C-branches for therapy and diagnosis | BAYER AG (DE) | 1995-04-05 | — | — | EP | disclosed |