Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319779 | 0.84 | MAPT (0.46) | POLBRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8319090 | 0.84 | MAPT (0.46) | POLBRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5313843 | 0.73 | KDM4E (0.42) | RAB9AKMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL1932513 | 0.71 | MEN1 (0.55) | POLBRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL16971212 | 0.71 | POLB (0.44) | POLBRAB9AMEN1KMT2ACA12 | |
| SCHEMBL4703943 | 0.71 | KMT2A (0.43) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL12869663 | 0.71 | ALDH1A1 (0.44) | POLBRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8319773 | 0.70 | MEN1 (0.47) | POLBRAB9AMEN1KMT2ACA12 | |
| SCHEMBL1019784 | 0.69 | MEN1 (0.71) | POLBRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6677087 | 0.69 | MEN1 (0.71) | POLBRAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944596-A1 | SECO PRECURSORS OF CYCLOPROPYLINDOLINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025898-A1 | SECO PRECURSORS OF CYCLOPROPYLINDOLINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-06-18 | — | — | WO | disclosed |