Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119360 | 0.80 | MRGPRX4 (0.48) | LMNATP53CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL4689675 | 0.79 | CSNK2A1 (0.55) | LMNATP53MEN1KMT2ANPSR1 | |
| SCHEMBL4688982 | 0.79 | CSNK2A1 (0.55) | LMNATP53MEN1KMT2ANPSR1 | |
| SCHEMBL9291695 | 0.78 | TP53 (0.45) | LMNATP53MEN1KMT2ANPSR1 | |
| SCHEMBL3725628 | 0.77 | TP53 (0.58) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12677545 | 0.76 | NPSR1 (0.68) | LMNANPSR1CYP1A2KDM4EAGTR1 | |
| SCHEMBL8288364 | 0.76 | NPSR1 (0.68) | LMNANPSR1CYP1A2KDM4EAGTR1 | |
| SCHEMBL12677544 | 0.76 | NPSR1 (0.68) | LMNANPSR1CYP1A2KDM4EAGTR1 | |
| SCHEMBL10432959 | 0.75 | CYP1A2 (0.62) | LMNAMEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL8297293 | 0.74 | CA2 (0.45) | LMNATP53MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661281-B1 | Substituted phenylethers as pesticides | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | disclosed |
| US-5663379-A | AGROCHEMICAL ACTIVE INGREDIENTS | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0661281-A1 | Substituted phenylethers as pesticides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |