SCHEMBL9119360

SCHEMBL9119360

CC(C)COCc1ccc(OCc2ccc(Cl)cc2)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 9/20 0.48
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
CCR5 P51681 5/20 0.44
HPGD P15428 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
GAA P10253 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
PDK2 Q15119 1/20 0.43
TACR2 P21452 1/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9291695 0.90 TP53 (0.45) MRGPRX4LMNATP53HPGDNPC1
SCHEMBL12153202 0.83 HTT (0.53) HPGDRAB9ASMN1; SMN2GAAUSP2
SCHEMBL8301208 0.80 LMNA (0.52) LMNATP53HPGDNPC1RAB9A
SCHEMBL13321693 0.78 MRGPRX4 (0.71) MRGPRX4CCR5HPGDNPC1RAB9A
SCHEMBL9117350 0.75 MRGPRX4 (0.49) MRGPRX4CCR5HPGDNPC1RAB9A
SCHEMBL8414105 0.75 SMN1; SMN2 (0.53) MRGPRX4LMNATP53HPGDNPC1
SCHEMBL8297293 0.74 CA2 (0.45) LMNATP53HPGDNPC1RAB9A
SCHEMBL11460696 0.74 PPARD (0.55) MRGPRX4LMNATP53HPGDNPC1
SCHEMBL647273 0.74 CA1 (0.44) HPGDNPC1RAB9ASMN1; SMN2GAA
SCHEMBL9967704 0.73 KDM1A (0.56) LMNATP53HPGDSMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0504812-B1 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1995-09-06 EP claimed
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US claimed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US claimed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP claimed