Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655088 | 0.82 | TP53 (0.55) | MAPTSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL20618548 | 0.81 | EPHX2 (0.58) | CHRM4SMN1; SMN2ADORA2AMEN1KMT2A | |
| SCHEMBL29105291 | 0.80 | CHRM4 (0.48) | POLBMAPTCHRM4SMN1; SMN2RECQL | |
| SCHEMBL30613362 | 0.80 | CHRM4 (0.48) | POLBMAPTCHRM4SMN1; SMN2RECQL | |
| SCHEMBL8300733 | 0.79 | LMNA (0.55) | USP2HPGDKDM4EALDH1A1CA1 | |
| SCHEMBL8292287 | 0.79 | GAA (0.57) | USP2HPGDKDM4EALDH1A1CA1 | |
| SCHEMBL30613368 | 0.78 | MEN1 (0.55) | POLBMAPTSMN1; SMN2MEN1PABPC1 | |
| SCHEMBL29105307 | 0.78 | MEN1 (0.55) | POLBMAPTSMN1; SMN2MEN1PABPC1 | |
| SCHEMBL8292555 | 0.77 | F10 (0.46) | POLBMAPTSMN1; SMN2RECQLUSP2 | |
| SCHEMBL8292547 | 0.77 | F10 (0.46) | POLBMAPTSMN1; SMN2RECQLUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |