Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292287 | 0.91 | GAA (0.57) | LMNAHPGDCA1CA2DNMT3A | |
| SCHEMBL7655088 | 0.84 | TP53 (0.55) | LMNAHPGDCA1CA2KDM4E | |
| SCHEMBL8292510 | 0.83 | AKR1B1 (0.51) | LMNAHPGDDNMT3AKDM4EUSP2 | |
| SCHEMBL17241767 | 0.81 | GAA (0.57) | LMNAHPGDDNMT3AAPEX1KDM4E | |
| SCHEMBL8299247 | 0.80 | PDE5A (0.53) | LMNAHPGDAKR1B1 | |
| SCHEMBL6944281 | 0.79 | GAA (0.55) | LMNAHPGDAPEX1KDM4EUSP2 | |
| SCHEMBL8301468 | 0.79 | POLB (0.51) | LMNAHPGDCA1CA2APEX1 | |
| SCHEMBL6940100 | 0.79 | MEN1 (0.52) | LMNAAKR1B1 | |
| SCHEMBL23535641 | 0.79 | KMT2A (0.53) | LMNAHPGDCA1CA2KDM4E | |
| SCHEMBL11445600 | 0.79 | LMNA (0.63) | LMNAHPGDDNMT3AAPEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| CN-1118595-A | Anthranilic acid derivative | EISAI CO LTD (JP) | 1996-03-13 | — | — | CN | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |