Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11669981 | 0.91 | TAAR1 (0.46) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL8722410 | 0.91 | TAAR1 (0.46) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL7438849 | 0.85 | TAAR1 (0.42) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL321367 | 0.85 | TAAR1 (0.45) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL29076614 | 0.82 | TAAR1 (0.50) | MEN1KMT2ATAAR1 | |
| SCHEMBL23015073 | 0.82 | ALDH1A1 (0.45) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL8306211 | 0.82 | MEN1 (0.53) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL27873875 | 0.81 | TDP1 (0.53) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL9407052 | 0.81 | TDP1 (0.53) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL8553636 | 0.81 | TDP1 (0.53) | MEN1KMT2AUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915843-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSES | SMITHKLINE BEECHAM PLC (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997041098-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-06 | — | — | WO | disclosed |