Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303553 | 0.87 | RARB (0.57) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL8303492 | 0.87 | RAB9A (0.50) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL8541255 | 0.85 | RAB9A (0.48) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL7610004 | 0.83 | MAPT (0.81) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL8304830 | 0.83 | RAB9A (0.54) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL11522518 | 0.81 | MAPT (0.63) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL32663699 | 0.81 | MAPT (0.69) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL11376570 | 0.81 | MAPT (0.65) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL7602089 | 0.80 | SMN1; SMN2 (0.81) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL22103875 | 0.80 | RAB9A (0.76) | MAPTRAB9ASMN1; SMN2TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462578-B1 | Mesomorphic compound for use in liquid crystal composition and liquid crystal device and display apparatus using same | CANON KK (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5244596-A | Benzoxazoles | CANON KABUSHIKI KAISHA (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0462578-A1 | Mesomorphic compound for use in liquid crystal composition and liquid crystal device and display apparatus using same | CANON KABUSHIKI KAISHA (JP) | 1991-12-27 | — | — | EP | disclosed |