Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 8/20 | 0.40 |
| ▸ | AR | P10275 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10860792 | 0.90 | MAP4K4 (0.52) | MAP4K4PRKCDMINK1CYP1A2NPSR1 | |
| SCHEMBL10857138 | 0.84 | VDR (0.42) | CYP1A2KDM4EAGTR1LMNAVDR | |
| SCHEMBL10856565 | 0.80 | AR (0.50) | CYP1A2NPSR1CYP2D6KDM4EAGTR1 | |
| SCHEMBL10859888 | 0.77 | TSHR (0.47) | CYP1A2KDM4EVDRARTSHR | |
| SCHEMBL8959153 | 0.77 | GLA (0.48) | TSHR | |
| SCHEMBL12677545 | 0.76 | NPSR1 (0.68) | CYP1A2NPSR1CYP2D6KDM4EAGTR1 | |
| SCHEMBL8288364 | 0.76 | NPSR1 (0.68) | CYP1A2NPSR1CYP2D6KDM4EAGTR1 | |
| SCHEMBL12677544 | 0.76 | NPSR1 (0.68) | CYP1A2NPSR1CYP2D6KDM4EAGTR1 | |
| SCHEMBL8865546 | 0.76 | CYP1A2 (0.47) | MAP4K4PRKCDMINK1CYP1A2NPSR1 | |
| SCHEMBL10432959 | 0.75 | CYP1A2 (0.62) | CYP1A2NPSR1CYP2D6KDM4EAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661281-B1 | Substituted phenylethers as pesticides | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | disclosed |
| US-5663379-A | AGROCHEMICAL ACTIVE INGREDIENTS | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0661281-A1 | Substituted phenylethers as pesticides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |