SCHEMBL8959153

SCHEMBL8959153

CCC(C)Oc1ccc(OCCN)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CSNK2A1 P68400 4/20 0.46
PPARD Q03181 2/20 0.39
PPARA Q07869 2/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 1/20 0.39
NLRP1 Q9C000 1/20 0.39
PLAU P00749 1/20 0.38
BACE1 P56817 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959042 0.87 CSNK2A1 (0.50) GLASMN1; SMN2CSNK2A1PPARDPPARA
SCHEMBL9855837 0.78 TAAR1 (0.48) SMN1; SMN2
SCHEMBL9119032 0.78 MRGPRX4 (0.49) SMN1; SMN2HPGD
SCHEMBL9117119 0.78 MRGPRX4 (0.43) SMN1; SMN2CSNK2A1PPARDPPARAHPGD
SCHEMBL8301633 0.77 MAP4K4 (0.47) TSHR
SCHEMBL9119277 0.77 MRGPRX4 (0.43) SMN1; SMN2HPGD
SCHEMBL9586217 0.77 MRGPRX4 (0.47) PPARDPPARA
SCHEMBL9503004 0.76 L3MBTL1 (0.44) GLASMN1; SMN2HPGDTSHRNLRP1
SCHEMBL9292010 0.76 APP (0.46) SMN1; SMN2HPGD
SCHEMBL9292640 0.76 CCR5 (0.45) SMN1; SMN2HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed