Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747113 | 1.00 | KMT2A (0.35) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL21747114 | 0.93 | KMT2A (0.33) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL30170170 | 0.87 | KMT2A (0.41) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL18631592 | 0.87 | KMT2A (0.41) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL8324848 | 0.84 | DPP4 (0.35) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL21157404 | 0.83 | KMT2A (0.34) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL21156668 | 0.83 | KMT2A (0.33) | KMT2AMEN1GAACTSSCTSK | |
| SCHEMBL15535916 | 0.82 | KMT2A (0.48) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL27978333 | 0.82 | KMT2A (0.48) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL8299304 | 0.82 | KMT2A (0.48) | KMT2AMEN1GAAMAPK1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658066-B9 | ADAMANTYLGLYCINE- BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FOR THE TREATMENT OF DIABETES | BRISTOL MYERS SQUIBB CO (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-1658066-B1 | ADAMANTYLGLYCINE- BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FOR THE TREATMENT OF DIABETES | BRISTOL MYERS SQUIBB CO (US) | 2009-09-30 | — | — | EP | disclosed |
| WO-2005012249-A2 | ADAMANTYGLYCINE- BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FOR THE TREATMENT OF DIABETES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-10 | — | — | WO | disclosed |