Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978333 | 1.00 | KMT2A (0.48) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL8299304 | 1.00 | KMT2A (0.48) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL30170170 | 0.94 | KMT2A (0.41) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL18631592 | 0.94 | KMT2A (0.41) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL24815908 | 0.86 | KMT2A (0.39) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL2110140 | 0.86 | KMT2A (0.39) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL2549745 | 0.86 | KMT2A (0.39) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL27218008 | 0.86 | KMT2A (0.39) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL8271718 | 0.86 | KMT2A (0.39) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL27218038 | 0.86 | KMT2A (0.39) | KMT2AMEN1MAPK1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759075-B1 | COMPOUNDS WITH FERROPTOSIS INDUCING ACTIVITY AND METHODS OF THEIR USE | FERRO THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |
| US-20240197666-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-GEN THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | US | disclosed |
| EP-4313095-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-Gen Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117098544-A | Diterpenoid compounds acting on Protein Kinase C (PKC) | K-GEN治疗股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-20230312571-A1 | RING-MODIFIED PROLINE SHORT PEPTIDE COMPOUND AND USE THEREOF | FUJIAN AKEYLINK BIOTECHNOLOGY CO., LTD. (CN) | 2023-10-05 | — | — | US | disclosed |
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2023-02-09 | — | — | US | disclosed |
| US-20220411362-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-GEN THERAPEUTICS, INC. | 2022-12-29 | — | — | US | disclosed |
| CN-112824398-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| EP-4041268-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-Gen, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114786697-A | Diterpenoids acting on Protein Kinase C (PKC) | K-GEN股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-112341439-A | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112041301-A | Compounds having iron death inducing activity and methods of use thereof | 费罗治疗公司 | 2020-12-04 | — | — | CN | disclosed |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | MOLECULAR SKIN THERAPEUTICS, INC. | 2019-08-29 | — | — | US | disclosed |
| US-9416105-B2 | Process for preparation of saxagliptin and its hydrochloride salt | AMNEAL PHARMACEUTICALS LLC (US) | 2016-08-16 | — | — | US | disclosed |
| US-20160194282-A1 | A Process For Preparation Of Saxagliptin And Its Hydrochloride Salt | AMNEAL PHARMACEUTICALS LLC | 2016-07-07 | — | — | US | disclosed |
| US-9199933-B2 | Process for preparation of (1S, 3S, 5S)-2-[(2S)-2-amino-2-(3-hydroxy-I-adamantyl) acetyl]-2-azabicyclo [3.1.0] hexane-3-carbonitrile | Davuluri, Ramamohan Rao (IN) | 2015-12-01 | — | — | US | disclosed |
| US-20150112084-A1 | PROCESS FOR PREPARATION OF (IS, 3S, 5S)-2-[(2S)-2-AMIN0-2-(3-HYDROXY-l-ADAMANTYL) ACETYL]-2-AZABICYCLO [3.1.0] HEXANE-3-CARBONITRILE | DAVULURI, RAMAMOHAN RAO (IN) | 2015-04-23 | — | — | US | disclosed |
| WO-2015031595-A1 | A PROCESS FOR PREPARATION OF SAXAGLIPTIN AND ITS HYDROCHLORIDE SALT | AMNEAL PHARMACEUTICALS LLC (US) | 2015-03-05 | — | — | WO | disclosed |
| US-20150038672-A1 | Modular Imaging Agents Containing Amino Acids and Peptides | ROCHESTER INSTITUTE OF TECHNOLOGY (US) | 2015-02-05 | — | — | US | disclosed |
| WO-2013175395-A2 | IMPROVED PROCESS FOR PREPARATION OF SAXAGLIPTIN AND ITS SALTS | DR. REDDYS LABORATORIES LIMITED (IN) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038672-A1 | Modular Imaging Agents Containing Amino Acids and Peptides | SLC43A1, TAP1, TTR | KMT2A 1695/4885MEN1 91/4885MAPK1 1668/4885 |
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | KMT2A 2510/4885MEN1 1772/4885MAPK1 3912/4885 |
| US-20160194282-A1 | A Process For Preparation Of Saxagliptin And Its Hydrochloride Salt | DPP4, SLC5A1, DPP9 | KMT2A 2763/4885MEN1 2544/4885MAPK1 334/4885 |
| US-20230312571-A1 | RING-MODIFIED PROLINE SHORT PEPTIDE COMPOUND AND USE THEREOF | VIP, PREP, PRAP1 | KMT2A 3623/4885MEN1 1707/4885MAPK1 998/4885 |
| US-20220411362-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | PRKCA, PRKCH, PRKCB | KMT2A 2943/4885MEN1 3968/4885MAPK1 1188/4885 |
| US-20150112084-A1 | PROCESS FOR PREPARATION OF (IS, 3S, 5S)-2-[(2S)-2-AMIN0-2-(3-HYDROXY-l-ADAMANTYL) ACETYL]-2-AZABICYCLO [3.1.0] HEXANE-3-CARBONITRILE | DPP4, DPP3, DPP9 | KMT2A 4548/4885MEN1 1723/4885MAPK1 1324/4885 |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | AIFM2, GPX4, GPX1 | KMT2A 2475/4885MEN1 1681/4885MAPK1 3769/4885 |
| US-20240197666-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | PRKCA, PRKCB, PRKCI | KMT2A 3236/4885MEN1 4010/4885MAPK1 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.