Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301472 | 0.85 | MEN1 (0.59) | PKMLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8293880 | 0.78 | HSP90AA1 (0.61) | PKMLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8567528 | 0.76 | HSD17B10 (0.66) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL14267566 | 0.75 | HSP90AA1 (0.56) | PKMMAPTLMNAUSP2SMN1; SMN2 | |
| SCHEMBL8298680 | 0.72 | HSP90AA1 (0.48) | PKMLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL27480077 | 0.72 | TDP1 (0.57) | PKMLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9231471 | 0.72 | HSD17B10 (0.59) | PKMMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL8297954 | 0.71 | PKM (0.68) | PKMLMNAUSP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8301386 | 0.71 | MEN1 (0.62) | PKMLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8566730 | 0.70 | HPGD (0.47) | PKMMAPTUSP2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |