Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298680 | 0.88 | HSP90AA1 (0.48) | HPGDPOLBKMT2APKMTSHR | |
| SCHEMBL8291729 | 0.88 | LMNA (0.51) | HPGDPOLBKMT2APKMTSHR | |
| SCHEMBL8291728 | 0.84 | HPGD (0.49) | HPGDPOLBKMT2APKMTSHR | |
| SCHEMBL8299687 | 0.83 | LMNA (0.44) | HPGDPOLBKMT2APKMTSHR | |
| SCHEMBL8299688 | 0.83 | LMNA (0.44) | HPGDPOLBKMT2APKMTSHR | |
| SCHEMBL8292507 | 0.83 | HPGD (0.48) | HPGDPOLBKMT2APKMTSHR | |
| SCHEMBL8574890 | 0.81 | KMT2A (0.47) | HPGDPOLBKMT2APKMTSHR | |
| SCHEMBL8301638 | 0.79 | PKM (0.56) | HPGDPOLBKMT2APKMTSHR | |
| SCHEMBL8572705 | 0.78 | KDM4E (0.48) | HPGDPOLBKMT2ATSHRKDM4E | |
| SCHEMBL8570583 | 0.78 | KMT2A (0.44) | HPGDPOLBKMT2APKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |