Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301808 | 1.00 | RAB9A (0.68) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL9170782 | 0.87 | RAB9A (0.89) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL9170780 | 0.87 | RAB9A (0.89) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL10773654 | 0.84 | RAB9A (0.69) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL10773660 | 0.84 | RAB9A (0.69) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL7502713 | 0.84 | CYSLTR2 (0.63) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL7502719 | 0.84 | CYSLTR2 (0.63) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL9704021 | 0.82 | RAB9A (0.74) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL30708723 | 0.82 | RAB9A (0.74) | RAB9AKDM4ENPC1LMNAPKM | |
| SCHEMBL8306853 | 0.82 | CYSLTR1 (0.45) | RAB9AKDM4ENPC1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469833-B1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY CO ELI (GB) | 1999-09-08 | — | — | EP | disclosed |
| CN-1040108-C | Pharmaceutical compounds | LILLY INDUSTRIES LTD (GB) | 1998-10-07 | — | — | CN | disclosed |
| US-5281593-A | Pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| CN-1061413-A | Medicinal compound | LILLY INDUSTRIES LTD (GB) | 1992-05-27 | — | — | CN | disclosed |
| EP-0469833-A1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |