SCHEMBL9704021

SCHEMBL9704021

Clc1ccc(C=Cc2ccc3ccccc3n2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.74
NPC1 O15118 8/20 0.74
KDM4E B2RXH2 7/20 0.74
LMNA P02545 6/20 0.74
PKM P14618 2/20 0.74
MAPT P10636 6/20 0.71
L3MBTL1 Q9Y468 5/20 0.71
MEN1 O00255 5/20 0.71
KMT2A Q03164 5/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
ALDH1A1 P00352 1/20 0.71
MAPK1 P28482 3/20 0.65
RXFP1 Q9HBX9 1/20 0.65
HTT P42858 2/20 0.61
CYSLTR2 Q9NS75 2/20 0.56
CYSLTR1 Q9Y271 2/20 0.56
GLA P06280 2/20 0.56
TDP1 Q9NUW8 3/20 0.53
ECE2 P0DPD6 2/20 0.53
NFKB1 P19838 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30708723 1.00 RAB9A (0.74) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL9170782 0.91 RAB9A (0.89) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL9170780 0.91 RAB9A (0.89) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL659666 0.85 RAB9A (1.00) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL659665 0.85 RAB9A (1.00) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL30708719 0.85 RAB9A (1.00) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL28443608 0.83 RAB9A (0.80) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL8617773 0.83 RAB9A (1.00) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL9594355 0.83 RAB9A (1.00) RAB9ANPC1KDM4ELMNAPKM
SCHEMBL1899504 0.83 RAB9A (0.74) RAB9ANPC1KDM4ELMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283756-B Preparation method of N-heteroaryl stilbene compound 常州大学 2025-06-24 CN disclosed
CN-116804026-B Method for preparing beta-silyl aza-aromatic compound by catalysis of chitosan Schiff base copper-based functional material 湖北工程学院 2025-02-11 CN disclosed
CN-117924166-A Direct alkenylation of methylazaheteroaryl compounds and benzyl alcohols 常州大学 2024-04-26 CN disclosed
CN-116804026-A Method for preparing beta-silyl aza-aromatic compound by catalysis of chitosan Schiff base copper-based functional material 湖北工程学院 2023-09-26 CN disclosed
CN-116283756-A Preparation method of N-heteroaryl stilbene compound 常州大学 2023-06-23 CN disclosed
EP-0220589-B1 PHOTOPOLYMERISABLE COMPOUND AND REGISTRATION MATERIAL CONTAINING IT HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
US-4737445-A 2,3-DIHYDRO-1H-CYCLOPENTA(B)QUINOLINE HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-12 US disclosed
EP-0220589-A2 Photopolymerisable compound and registration material containing it HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-06 EP disclosed
EP-0028749-B1 PHOTOPOLYMERISABLE COMPOSITION AND PHOTOPOLYMERISABLE RECORDING MATERIAL MADE THEREWITH HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-07 EP disclosed
EP-0011786-B1 PHOTOPOLYMERISABLE COMPOSITION HOECHST AKTIENGESELLSCHAFT (DE) 1983-01-19 EP disclosed
US-4304841-A DISULFIDE COMPOUND TO LOWER SENSITIVITY TO OXYGEN HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-08 US disclosed
US-4272609-A 2-ALKENYL QUINOLINE PHOTOINITIATOR HOECHST AKTIENGESELLSCHAFT (DE) 1981-06-09 US disclosed
EP-0028749-A2 Photopolymerisable composition and photopolymerisable recording material made therewith HOECHST AKTIENGESELLSCHAFT (DE) 1981-05-20 EP disclosed
EP-0021429-A2 Photopolymerisable copy material and process for making relief images HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-07 EP disclosed
EP-0011786-A2 Photopolymerisable composition HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-11 EP disclosed