Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.76 |
| ▸ | HTR1A | P08908 | 2/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.76 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.76 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.76 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.76 |
| ▸ | DRD1 | P21728 | 2/20 | 0.76 |
| ▸ | HTR2A | P28223 | 2/20 | 0.76 |
| ▸ | HTR2C | P28335 | 2/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.76 |
| ▸ | HRH1 | P35367 | 2/20 | 0.76 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.76 |
| ▸ | DRD3 | P35462 | 2/20 | 0.76 |
| ▸ | HTR2B | P41595 | 2/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.76 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12287533 | 0.93 | DRD2 (0.80) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL8203956 | 0.89 | DRD2 (0.78) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL14198437 | 0.88 | DRD2 (0.88) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL15042307 | 0.88 | DRD2 (0.67) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL2369600 | 0.88 | DRD2 (0.67) | DRD2LMNACHRM2HTR1AADRA2A | |
| Quetiapine SCHEMBL2537668 | 0.88 | DRD2 (0.94) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL13114628 | 0.87 | DRD2 (0.78) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL16884483 | 0.87 | DRD2 (0.74) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL2397332 | 0.86 | DRD2 (0.65) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL15042241 | 0.86 | DRD2 (0.65) | DRD2LMNACHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028457-A1 | PREPARATION OF QUETIAPINE | FERMION OY (FI) | 2005-03-31 | — | — | WO | disclosed |