Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303763 | 0.85 | GALR3 (0.46) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL8307878 | 0.83 | HTT (0.54) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL9185972 | 0.82 | CCNC (0.51) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL16997382 | 0.77 | PDE5A (0.57) | SMN1; SMN2 | |
| SCHEMBL8303441 | 0.76 | HTT (0.47) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL15684987 | 0.76 | RAB9A (0.60) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL9085869 | 0.74 | GALR3 (0.45) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL29236604 | 0.74 | HTT (0.36) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL17133553 | 0.73 | PDE2A (0.47) | AURKAAURKBHTTLMNAEGFR | |
| SCHEMBL8308405 | 0.73 | CNR1 (0.53) | AURKAAURKBHTTGALR3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555388-B1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | DU PONT (US) | 1999-01-27 | — | — | EP | claimed |
| US-5378708-A | Agricultural pesticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-03 | — | — | US | claimed |
| EP-0555388-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-18 | — | — | EP | claimed |
| WO-1992008704-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | claimed |
| EP-0555388-B1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | DU PONT (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5378708-A | Agricultural pesticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0555388-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992008704-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |