Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236657 | 0.85 | METAP1 (0.43) | HTTGALR3SMN1; SMN2RAB9AMETAP2 | |
| SCHEMBL29236576 | 0.83 | METAP1 (0.40) | HTTSMN1; SMN2METAP2METAP1LMNA | |
| SCHEMBL29882152 | 0.82 | GAA (0.37) | HTTSMN1; SMN2RAB9ALMNACYP1A2 | |
| SCHEMBL28673572 | 0.82 | GAA (0.37) | HTTSMN1; SMN2RAB9ALMNACYP1A2 | |
| SCHEMBL8307878 | 0.81 | HTT (0.54) | HTTGALR3SMN1; SMN2RAB9AMETAP2 | |
| SCHEMBL29236832 | 0.80 | CRHR1 (0.38) | HTTGALR3SMN1; SMN2RAB9ALMNA | |
| SCHEMBL29236659 | 0.79 | HTT (0.34) | HTTGALR3SMN1; SMN2RAB9AMETAP2 | |
| SCHEMBL29236581 | 0.77 | GALR3 (0.35) | HTTGALR3SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL9403797 | 0.76 | MPO (0.40) | HTTSMN1; SMN2RAB9ALMNAMAPK1 | |
| SCHEMBL8303441 | 0.76 | HTT (0.47) | HTTGALR3SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206527-A | N-pyridine ethyl pyrimidine amine compound | 湖南化工研究院有限公司 | 2024-06-18 | — | — | CN | claimed |