Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308995 | 0.87 | TNFRSF1A (0.43) | TNFRSF1ARARGRARARARBRXRA | |
| SCHEMBL3637333 | 0.84 | TNFRSF1A (0.56) | TNFRSF1ARARGRARARARBTPMT | |
| SCHEMBL13705717 | 0.78 | RXRA (0.50) | TNFRSF1ARARGRARARARBRXRA | |
| SCHEMBL7792403 | 0.78 | TNFRSF1A (0.48) | TNFRSF1ARARGRARARARBTPMT | |
| SCHEMBL7792476 | 0.75 | TNFRSF1A (0.46) | TNFRSF1ARARGRARARARBTPMT | |
| SCHEMBL10322781 | 0.74 | TNFRSF1A (0.45) | TNFRSF1ARARGRARARARBTPMT | |
| SCHEMBL7796475 | 0.74 | TNFRSF1A (0.48) | TNFRSF1ARARGRARARARBRXRA | |
| SCHEMBL9396541 | 0.74 | TSHR (0.44) | TNFRSF1ARARGRARARARBTPMT | |
| SCHEMBL2772941 | 0.73 | TNFRSF1A (0.53) | TNFRSF1ARARGRARARARBRXRA | |
| SCHEMBL10323062 | 0.73 | TNFRSF1A (0.44) | TNFRSF1ARARGRARARARBTPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089922-A2 | CALCIUM CHANNEL INHIBITORS COMPRISING BENZHYDRIL SPACED FROM PIPERAZINE | NEUROMED TECHNOLOGIES, INC. (CA) | 2004-10-21 | — | — | WO | disclosed |