Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 7/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296430 | 0.87 | PDGFRB (0.56) | PDGFRBPDGFRAALDH1A1GRM5PLAU | |
| SCHEMBL18253192 | 0.81 | ALDH1A1 (0.65) | PDGFRBPDGFRAALDH1A1GRM5APP | |
| SCHEMBL29827843 | 0.76 | ABL1 (0.42) | PDGFRBPDGFRAALDH1A1GRM5PTGDR2 | |
| SCHEMBL26613541 | 0.75 | PDGFRB (0.54) | PDGFRBPDGFRAALDH1A1ADORA3ADORA1 | |
| SCHEMBL26003354 | 0.74 | PDGFRB (0.52) | PDGFRBPDGFRAALDH1A1GRM5APP | |
| SCHEMBL11306433 | 0.73 | ABL1 (0.53) | PTGDR2 | |
| SCHEMBL31060615 | 0.72 | PDGFRB (1.00) | PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL16288953 | 0.72 | PDGFRB (0.39) | PDGFRBPDGFRAALDH1A1ADORA3ADORA1 | |
| SCHEMBL13516538 | 0.69 | GRM5 (0.61) | GRM5PLAUPLATADKAPP | |
| SCHEMBL21858115 | 0.69 | ALDH1A1 (0.58) | PDGFRBPDGFRAALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508469-B1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5493024-A | 1,2-DIARYL-2-PROPEN-1-ONE CHEMICAL INTERMEDIATE COMPOUND | DOWELANCO (US) | 1996-02-20 | — | — | US | disclosed |
| US-5250532-A | Moths. termites | DOWELANCO (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0508469-A1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1992-10-14 | — | — | EP | disclosed |