Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.59 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15112998 | 0.86 | ALDH1A1 (0.58) | ALDH1A1PDGFRBPDGFRAACACBGRM5 | |
| SCHEMBL3061440 | 0.86 | ALDH1A1 (0.58) | ALDH1A1PDGFRBPDGFRAACACBCYP1A2 | |
| SCHEMBL21858115 | 0.86 | ALDH1A1 (0.58) | ALDH1A1PDGFRBPDGFRAACACBGRM5 | |
| SCHEMBL7214768 | 0.83 | ALDH1A1 (0.63) | ALDH1A1PDGFRBPDGFRAACACBCYP1A2 | |
| SCHEMBL4818276 | 0.83 | ALDH1A1 (0.63) | ALDH1A1PDGFRBPDGFRAACACBCYP1A2 | |
| SCHEMBL18253193 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PDGFRBPDGFRAACACBGRM5 | |
| SCHEMBL15114977 | 0.82 | ALDH1A1 (0.57) | ALDH1A1PDGFRBPDGFRAACACBCYP1A2 | |
| SCHEMBL20593929 | 0.81 | ALDH1A1 (0.56) | ALDH1A1PDGFRBPDGFRAACACBCYP1A2 | |
| SCHEMBL8302360 | 0.81 | PDGFRB (0.56) | ALDH1A1PDGFRBPDGFRAGRM5APP | |
| SCHEMBL8296430 | 0.81 | PDGFRB (0.56) | ALDH1A1PDGFRBPDGFRAACACBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190099747-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | UNIV CALIFORNIA (US) | 2019-04-04 | — | — | US | disclosed |
| US-9956551-B2 | Nano-to-nano Fe/ppm Pd catalysis of cross-coupling reactions in water | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-01 | — | — | US | disclosed |
| US-9956551-B2 | Nano-to-nano Fe/ppm Pd catalysis of cross-coupling reactions in water | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170341069-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | UNIV CALIFORNIA (US) | 2017-11-30 | — | — | US | disclosed |
| US-20170341069-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | UNIV CALIFORNIA (US) | 2017-11-30 | — | — | US | disclosed |
| US-20160339418-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | LIPSHUTZ BRUCE H (US) | 2016-11-24 | — | — | US | disclosed |
| US-20160339418-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | LIPSHUTZ BRUCE H (US) | 2016-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099747-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | SOD1, MPO, TFRC | ALDH1A1 2225/4885PDGFRB 2989/4885PDGFRA 2546/4885 |
| US-20160339418-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | SOD1, MPO, TFRC | ALDH1A1 2210/4885PDGFRB 3212/4885PDGFRA 2597/4885 |
| US-20170341069-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | SOD1, MPO, TFRC | ALDH1A1 2225/4885PDGFRB 2989/4885PDGFRA 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.